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Discontinuing Premarin

Q: I have been taking Premarin for over two years (after having a hysterectomy).  Two days ago, I decided to quit taking the medication after reading the recent reports.  What I want to know is if it is okay to quit taking this medication "cold turkey." Is this safe, as far as you know? I did not consult my doctor.   

Thank you, S.Y.

Dr. Donnica:
First of all, I always recommend contacting your prescribing physician before stopping or restarting ANY prescription medication. S/he would have first reassured you that there was no reason for you to stop taking your medication because of the recent news reports regarding the Women's Health Initiative findings. That study canceled the Prempro (Premarin PLUS medroxyprogesterone acetate) arm of the study due to increased serious adverse events, NOT the Premarin-only group. 

In other words, this news shouldn't really affect you. Ideally, when stopping any form of hormone replacement therapy, physicians recommend a weaning process, rather than a sudden stop.  For more information about the Women's Health Initiative results, click here.  For more information about hormone replacement therapy, click here.

Best regards,
Donnica L. Moore, MD
President, DrDonnica.com

Created: 9/15/2002  -  Donnica Moore, M.D.

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