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STAR Trial

Q: What is the STAR Trial?

Dr. Donnica:
The STAR trial is an on-going study launched in June 1999, by the National Surgical Adjuvant Breast and Bowel Project out of the National Cancer Institute (NCI).  The acronym stands for "Study of Tamoxifen and Raloxifene".  Both tamoxifen (Nolvadex) and raloxifene (Evista) are selective estrogen receptor modulators (SERM's), which have a role in prevention of breast cancer in women at high risk.  The STAR trial aims to enroll 22,000 postmenopausal women who are at increased risk for developing breast cancer. The goal of the study is to determine whether raloxifene is also effective in reducing breast cancer risk in high-risk women who have not had breast cancer, and whether this drug has benefits over tamoxifen or fewer side effects.  For more information on this trial, click here.

Created: 11/16/2000  -  Donnica Moore, M.D.

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